Exploratory metabolomic analysis for characterizing the metabolic profile of the urinary bladder under estrogen deprivation.

Using a PLS-DA VIP score threshold of 2, five highly significant differential metabolites were identified: 3, 5-tetradecadiencarnitine, C17-carnitine, cholic acid, glycocholic acid, and pyroglutamine ( Figure 5D , Supplementary Table S6 ).

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