Association of Lipoprotein (a) and Standard Modifiable Cardiovascular Risk Factors With Incident Myocardial Infarction: The Mass General Brigham Lp(a) Registry.

The key findings were that: (1) high Lp(a) was significantly associated with an increased risk of first AMI regardless of the presence or number of SMuRFs, and this association remained highly significant after adjusting for risk factors; and (2) the excess risk imparted by having a high Lp(a) was similar to the risk of having 2 SMuRFs.

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