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Trends of Antihypertensive Prescription Among US Adults From 2010 to 2019 and Changes Following Treatment Guidelines: Analysis of Multicenter Electronic Health Records.

J Am Heart Assoc · 2024 · PMC11179868 · PMID 38639340

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a decreasing trendno p-value reported
Despite a recommended increased use of dual therapy and FDC among patients with BP ≥140/90 mm Hg by the 2017 Hypertention Clinical Practice Guidelines, we observed a decreasing trend instead.

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an increasing trendno p-value reported
Discussion In this study of 1 074 314 patients in 15 academic health care institutions across the United States, we observed a higher proportion of uncontrolled hypertension among Black patients compared with patients of other races and an increasing trend of monotherapy and decreasing trends of FDC and polytherapy.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.