BRCA1/2 mutation carriers vs the general breast cancer population (N = 799,986): 21-gene assay-based molecular characterization.

A trend toward significance was observed with respect to BRCA mutation type, with recurrences among 1/32 [3.1%] patients with PVs in BRCA1 vs 8/48 [16.7%] of patients with PVs in BRCA2 , p = 0.078).

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For the proliferation gene group, the differences in each single-gene and the gene group score remained highly significant in both pre- and postmenopausal patients (Table 3 ).

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