CXCR5 along with CD45RO and PD-1 are markers for T follicular helper (Tfh) cells that play a key role in B cell maturation 22 and from CHMI 1 to 3 there was an increasing trend in this cell population, but it did not reach significance (Supplementary Fig 4 ).
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Repeat controlled human Plasmodium falciparum infections delay bloodstream patency and reduce symptoms.
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