Negative emotionality shapes the modulatory effects of ketamine and lamotrigine in subregions of the anterior cingulate cortex.

Transl Psychiatry · 2024 · PMC11189565 · PMID 38890270

Europe PMC DOI

hedged sentence

0.0840

closest p · 1.7× alpha

0.0840

boldest claim

The sentences

marginally significantp = 0.084so close (0.05 < p ≤ 0.1)

fMRI results The mixed ANCOVAs calculated for the subregions of the ACC showed the following results: Spontaneous brain activity in the sgACC showed a significant effect of time ( F (2, 132) = 14.21, p < 0.001, η p 2 = 0.18), a marginally significant interaction effect between time and group ( F (4, 132) = 2.12, p = 0.084, η p 2 = 0.06), and no main effect of group.

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