Deletion of an immune evasion gene, <i>steD</i>, from a live <i>Salmonella enterica</i> serovar Typhimurium vaccine improves vaccine responses in aged mice.

In the spleen, the number of tetramer + CD4 + T cells in CVD 1926 Δ steD -immunized mice was almost significantly different from mice that received PBS ( p = 0.055, Mann-Whitney test), with a 2.6-fold increase in the median number of cells as compared to PBS mice ( Figure 2B ).

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