A Novel Macrophage Subpopulation Conveys Increased Genetic Risk of Coronary Artery Disease.

Exposure of cells to ox-LDL resulted in a moderate increase in enhancer histone signals flanking this CRE (Figure 6 A) and highly significant increases in both the chromatin accessibility of this CRE ( P =3.3×10 −8 ) and MITF expression (average log2FC=0.39; P <2.2×10 −16 ).

also in 132,142 other papers