Studies have shown that lncRNA NEAT1 (lncNEAT1) was highly expressed in patients with SLE, 8 , 9 and we found that lncNEAT1 showed an increasing trend in cSLE. 10 LncNEAT1 contains two transcripts: lncNEAT1_ 1 (3.7 kb) and lncNEAT1_ 2 (23 kb), 10 , 11 , 12 but the expression levels of lncNEAT1_ 1 and lncNEAT1_2 in cSLE are not clear, and there are no studies on the relationship between lncNEAT1 expression and clinical characteristics of cSLE.
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Long noncoding nuclear enriched abundant transcript 1_2 is a promising biomarker for childhood-onset systemic lupus erythematosus.
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