Gellan gum-gelatin based cardiac models support formation of cellular networks and functional cardiomyocytes.

We detected an increasing trend in the expression of fibroblast growth factor 2 ( FGF-2 ) in vascular 3D co-culture whereas the expression remained constant in cardiovascular multiculture and decreased in myocardial co-culture.

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We detected an overall trend with more mature calcium dynamics in 3D myocardial co-culture producing strong and high frequency Ca 2+ signals (F i g. 6 F–I).

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