Barely Significant
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Effect of Sex and Flow Status on Outcomes After Surgical or Transcatheter Aortic Valve Replacement.

JACC Adv · 2024 · PMC11198680 · PMID 38938841

1
hedged sentence
0.0800
closest p · 1.6× alpha
0.0800
boldest claim

The sentences

a nonsignificant trendP = 0.08so close (0.05 < p ≤ 0.1)
When adjusting for known risk factors (age, coronary artery disease, hypertension, diabetes, atrial fibrillation, chronic obstructive pulmonary disease, chronic kidney disease ≥ moderate-severe, LVEF, mean gradient), this difference was no longer significant, but there was a nonsignificant trend toward higher risk of all-cause mortality in women with PLF undergoing SAVR compared to those undergoing TAVR (adjusted HR: 2.33 [95% CI: 0.91-5.98], P = 0.08).

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