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Investigating Novel Therapeutic Approaches for Idiopathic Short Stature: Targeting siRNA and Growth Hormone Delivery to the Growth Plate Using Exosome Nanoparticles.

Adv Sci (Weinh) · 2024 · PMC11200009 · PMID 38639394

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highly significantno p-value reported
A highly significant discovery was made, where we observed that CT‐Exos specifically targets the growth plate cartilage, delivering si‐ISSRL to suppress ISSRL expression and increasing the local GH concentration in the growth plate cartilage.

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