Gut Microbiome-Mediated Mechanisms in Alleviating Opioid Addiction with Aqueous Extract of <i>Anacyclus pyrethrum</i>.

Subsequent to withdrawal, our observations using the OFT demonstrated that the administration of a daily dose of 200 mg/kg of AEAP alone resulted in a highly significant increase in the number of central and total lines crossed (F (4,25) = 88.38, p < 0.05 and F (4,25) = 73.84, p < 0.05, respectively) ( Figure 4 A,B).

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