Barely Significant
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The Effect of Isotretinoin on Insulin Resistance and Serum Adiponectin Levels in Acne Vulgaris Patients: A Systematic Review and Meta-Analysis.

Clin Pract · 2024 · PMC11202953 · PMID 38921259

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might be significantno p-value reported
These findings have pathophysiological value and, indirectly, clinical value; the increase might be significant pathophysiologically, but there is no major clinical outcome.

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