Evolution of an Extended Pathogenicity Motif in VP2 of Infectious Pancreatic Necrosis Virus Isolates from Farmed Rainbow Trout in Turkey.

To assess the extent of the adaptation of IPNV to the host over time, a codon adaptation index (CAI) of a partial VP2 amino acid sequence of the Turkish IPNV trout isolates calculated a surge of the CAI towards the trout genome trending to >1.04 between 2013 and 2017, whereas a decreasing trend of adaptation was seen before 2013 ( Figure 6 ). 4.

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