Disease Severity and Cytokine Expression in the Rhinovirus-Induced First Wheezing Episode.

In our previous studies, we demonstrated differences in the cytokine responses between wheezing children infected with RV and RSV [ 8 ] and observed a decreasing trend in the cytokine responses in young wheezing children infected with both RV and human bocavirus 1 (HBoV1) compared to RV only [ 9 ], suggesting that there is a difference in the proposed bronchiolitis endotypes at the cellular level.

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