Risk of Seizure Aggravation after COVID-19 Vaccinations in Patients with Epilepsy.

Vaccines (Basel) · 2024 · PMC11209536 · PMID 38932322

Europe PMC DOI

hedged sentences

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

an overall trendp = 0.055so close (0.05 < p ≤ 0.1)

There was also an overall trend toward reduced seizure frequency after the second vaccination dose approaching statistical significance (1.13 vs. 1.87, t = 1.921; p = 0.055).

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just missed significancep = 0.055so close (0.05 < p ≤ 0.1)

This difference was seen in both types of vaccine (BNT162b2 and CoronaVac) and drug-resistant epilepsy, but just missed significance for the second dose (1.13 vs. 1.87, t = 1.921; p = 0.055).

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