Single cell analyses reveal the PD-1 blockade response-related immune features in hepatocellular carcinoma.

Despite what we found in the validation cohort, both the cytotoxicity and exhaustion of CD8 + T cells demonstrated a decreasing trend during the early phase of TSTR ( Figure S8 H), with cytotoxicity more associated with stress than exhaustion alone (Figure 7 B, Figure S8 H).

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