Controversy on the CONVINCE study findings: the PRO take.

However, despite a positive trend, cardiovascular risk reduction was not achieved in CONVINCE, whereas it was a primary finding in the European HDF Pooling project, with a mortality reduction of approximately 24%.

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In terms of secondary outcomes, there was an interesting trend suggesting a reduction in cardiovascular events, although no significant differences were observed in deaths from cardiovascular causes (HR 0.81 [0.49–1.33]) and/or other severe cardiovascular events (HR 1.07 [0.86–1.33]) between the hemodiafiltration and hemodialysis groups.

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