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Invasive pneumococcal disease in Latin America and the Caribbean: Serotype distribution, disease burden, and impact of vaccination. A systematic review and meta-analysis.

PLoS One · 2024 · PMC11210815 · PMID 38935748

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a decreasing trendno p-value reported
The distribution of serotypes by period shows a decreasing trend since 2010 for PCV10 serotypes, observed for every type of IPD infection.

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