Pharmacovigilance of esketamine nasal spray: an analysis of the FDA adverse event reporting system database.

Front Pharmacol · 2024 · PMC11211360 · PMID 38948465

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an increasing trendno p-value reported

Since the approval of ESK-NS from 2019, there has been an increasing trend in AEs, which peaked in 2023.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.