highly significantp < 0.05
There were highly significant increases in expression of the chemokines, cytokines and inflammatory markers Ccl2 ( p < 0.05), Tnf ( p < 0.05), Il1β ( p < 0.001), Il6 ( p < 0.001), Nlrp3 ( p < 0.001) and Nfkbia ( p < 0.001) in LPS‐treated mice relative to controls (Figures 1a and b ).