Co-immobilization of whole cells and enzymes by covalent organic framework for biocatalysis process intensification.

When the flow rate was further increased, the yield of D-allulose showed a decreasing trend, which could be attributed to the shortened contact time and reduced collision efficiency between the reactants and INU-NH 2 &E-NH 2 @NKCOF-141 at higher reactant flow rates 43 .

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