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Epidemiology of systemic sclerosis in Quebec, Canada: a population-based study.

Lancet Reg Health Am · 2024 · PMC11220520 · PMID 38962065

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an increasing trendno p-value reported
Interpretation We showed an increasing trend in SSc incidence and prevalence and a decline in SMR over a 25-year period in Quebec.

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a decreasing trendno p-value reported
The SMR for females over the study period was 3.29 (95% CI 3.14–3.45) with a peak SMR of 4.21 (95% CI 3.61–4.87) in 1996 and a decreasing trend over time to an SMR of 2.63 (95% CI 2.34–2.95) in 2019.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.