Cancer stem cells: advances in knowledge and implications for cancer therapy.

951 , 952 Addressing these challenges, a notable trend in targeted CSCs therapy involves drug delivery systems to optimize therapeutic effects and overcome treatment resistance. 953 – 955 Targeting CSCs treatment predominantly utilizes nanoparticles, liposomes, and polymer micelle, while pH-sensitive capsules, and aptamers are also prevalent (Fig. 11 )

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