Bioinformatics analysis of an immunotherapy responsiveness-related gene signature in predicting lung adenocarcinoma prognosis.

Moreover, we found that the IRRS negatively correlated with the IPS, the IPS of cytotoxic T-lymphocyte-associated protein 4 (CTLA4) was significantly higher in the low-IRRS group, but the IPS score of PD-1 did not quite reach statistical significance between these groups (P=0.06) ( Figure 7F,7G ).

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