* P ≤ 0.05 was considered statistically significant, ** P ≤ 0.01 very significant and *** P ≤ 0.001 highly significant.
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The p21CIP1-CDK4-DREAM axis is a master regulator of genotoxic stress-induced cellular senescence.
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* P ≤ 0.05 was considered statistically significant, ** P ≤ 0.01 very significant and *** P ≤ 0.001 highly significant.