Other metabolites, including 20α, 22β-dihydroxycholesterol, cholesterol sulfate, 21-hydroxypregnenolone, pregnanediol, 5α-pregnane-3,20-diol, and cortexolone, showed a decreasing trend in the COVID-19-A group compared with HCs.
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Dysregulated proteasome activity and steroid hormone biosynthesis are associated with mortality among patients with acute COVID-19.
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