Delocalized quinolinium-macrocyclic peptides, an atypical chemotype for CNS penetration.

Sci Adv · 2024 · PMC11235165 · PMID 38985859

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highly significantno p-value reported

Despite low levels of JW47 detected in the brain, the compound demonstrated highly significant neuroprotection in an experimental model of MS ( 12 ).

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