[ 195 ], although the endotoxin level in the serum of ALS patients showed an increasing trend, it did not reach a significant difference with the endotoxin level in healthy people, in contrast to the LBP and sDC14 levels, which were significantly increased in ALS, especially in individuals with the rapidly progressive form of the disease.
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The sentences
Therefore, it is clear that epigenetic mechanisms are highly significant in the development of neurodegenerative diseases.