A PNPLA3-Deficient iPSC-Derived Hepatocyte Screen Identifies Pathways to Potentially Reduce Steatosis in Metabolic Dysfunction-Associated Fatty Liver Disease.

Int J Mol Sci · 2024 · PMC11242544 · PMID 39000384

Europe PMC DOI

hedged sentence

0.9093

closest p · 18.2× alpha

0.9093

boldest claim

The sentences

tended toward significancep = 0.9093not close (p > 0.1)

Treatment with Src kinase inhibitors 4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo[3,4-d]-pyrimidine (PP1) and 4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]-pyrimidine PP2 tended toward significance ( p = 0.9093 and 0.1935, respectively) but displayed variation between replicate wells.

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