Time trend analysis of rare cancer incidence 2011-2018: Nationwide population-based cancer registries in Japan.

Digestive (rare) An increasing trend of adenocarcinoma of the small intestine from 2005 to 2015 was reported by Hiroshima PBCR in Japan. 15 This was likely due to the early detection of cases owing to the recent standardization and wider use of improved upper gastrointestinal endoscopy techniques (e.g., endoscopy with a combination of narrow‐band imaging, balloon‐assisted endoscopy, and capsule endoscopy 16 , 17 ).

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