7B ), yet an increasing trend was detected in the amygdala (Fig. 7D ).
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Systemic immune challenge exacerbates neurodegeneration in a model of neurological lysosomal disease.
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Overall, although a decreasing trend was observed in the total number of NeuN+ cells in the cortex of poly(I:C) treated WT and both MPS IIIA groups, when compared to saline-treated WT mice, no significant difference was detected across groups (Fig. 8 B).