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Reduced hepatic impairment study to evaluate pharmacokinetics and safety of zavegepant and to inform dosing recommendation for hepatic impairment.

Clin Transl Sci · 2024 · PMC11252018 · PMID 39014555

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a positive trendno p-value reported
A positive trend was observed between AUC 0−t , AUC 0−inf , and C max and aPTT for both participants with moderate hepatic impairment and normal hepatic function (Figure 2c ).

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