Controlled human hookworm infection remodels plasmacytoid dendritic cells and regulatory T cells towards profiles seen in natural infections in endemic areas.

Nat Commun · 2024 · PMC11252261 · PMID 39013877

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highly significantP < 0.001actually significant

However, when analyzed on cluster level, principal component analysis (PCA) revealed highly significant segregation of the immune profiles before and after hookworm infection (Fig. 2B , PERMANOVA P < 0.001).

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