Additionally, QTL mapping of the PSA phenotype revealed a highly significant 334-kb region on chr 7 [logarithm of the odds (LOD) score of 10.3]] that centered on pfcrt ( Fig. 4A ).
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A <i>Plasmodium falciparum</i> genetic cross reveals the contributions of <i>pfcrt</i> and <i>plasmepsin II/III</i> to piperaquine drug resistance.
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