Multi-omics analysis unveils immunosuppressive microenvironment in the occurrence and development of multiple pulmonary lung cancers.

Furthermore, through immune cell abundance analysis we found that the content of immune-suppressed cells such as exhausted cells and Tregs markedly increased in the high-risk stages, while NK cells showed a decreasing trend (Fig. 5d and Supplementary Figs. 10 - 11 ).

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