Systemic Thrombolysis is Still the First-Line Treatment for Unstable Pulmonary Embolism.

Additionally, an increasing trend of PE mortality cannot be attributed to the failure of ST, as only a minority of patients with unstable PE receive ST when indicated. 4 As such, Dr Rozenbaum’s statement that “for many, the use of ST is becoming unethical” may be an overstatement, even in the minority of facilities able to rapidly institute procedural interventions in hemodynamically unstable patients.

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