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Efficacy, safety and immunogenicity of the biosimilar etanercept compared to the reference formulation original etanercept in patients with rheumatoid arthritis: An open-label, randomized, comparative, multicenter study.

Medicine (Baltimore) · 2024 · PMC11272322 · PMID 39058806

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a notable trendno p-value reported
The results of the analysis, shown in Figure 3 , showed a notable trend towards a decrease in DAS28 (ESR and CRP) starting at week 4 after initiation of treatment with the investigational drug.

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