Transcriptionally induced nucleoid-associated protein-like <i>ccr1</i> in combined-culture serves as a global effector of <i>Streptomyces</i> secondary metabolism.

Although more detailed analysis may be required, ccr1 inactivation did not show a significant impact on apparent morphological differentiation in the tested strains A3(2) and HEK616, as judged by growing colonies on several agar plate conditions ( Supplementary Figure S2 ), which indicated that the observed effect was somewhat significant to SM production.

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