Primary SARS-CoV-2 infection in children and adults results in similar Fc-mediated antibody effector function patterns.

For ADNKA, we observed a strong absolute decrease in serum ADNKA capacity over time, which has previously been shown by others, as well as a decreasing trend in the relative ADNKA capacity of serum antibodies at later compared to earlier time points. 34 , 35 , 36 , 41 Unlike for ADCP, the relative ADNKA capacity did not appear to associate with IgG avidity, suggesting that other antibody characteristics are more important determinants of NK cell activity, at least in this experimental set‐up.

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