<sup>1</sup>H and <sup>31</sup>P Magnetic Resonance Spectroscopic Metabolomic Imaging: Assessing Mitogen-Activated Protein Kinase Inhibition in Melanoma.

Cells · 2024 · PMC11274771 · PMID 39056801

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a statistical trendp = 0.06so close (0.05 < p ≤ 0.1)

These data match the fact that WM983BR had a decreased but not significant tumor volume with trametinib treatment during our observation period, showing only a statistical trend ( p = 0.06, Figure 7 ).

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highly significantno p-value reported

Furthermore, the time-related differences in the tumor lactate and alanine content between the untreated and trametinib-treated groups in the WM983BR, WM983B, and DB-1 xenografts were highly significant (slope comparison p -value in Figure 5 ).

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