Inflammatory Cytokines and Clinical Outcome Following Biological Therapy in Adult Bio-Naïve Psoriasis Patients.

In another study demonstrating the efficacy of ustekinumab to reduce cardiovascular risk, the trend toward significance reduction in IL-17A and IL-23 could be seen at 12 weeks ( p < 0.1) from initiation of therapy, and a more significant reduction in these was achieved at week 52 [ 24 ].

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The limit of statistical significance was considered as p < 0.05, and a value of p > 0.05 but p < 0.1 was considered as a trend towards significance. 3.

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