On one hand, newer treatments confer better disease control and may reduce the absolute benefit from nodal radiation, but on the other hand, even a small benefit may be significant in these women since they are more likely to receive suboptimal systemic treatments because of advanced age and co-morbidities.
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Post-Operative Radiation in Early Breast Cancer with N1 Disease: 10-Year Follow-Up.
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The sentences
Therefore, there may not be significant benefits from radiotherapy outcomes in early breast cancer patients with N1 disease.