Network Pharmacology and Transcriptomics to Explore the Pharmacological Mechanisms of 20(S)-Protopanaxatriol in the Treatment of Depression.

In addition, the mice in the CUMS group had a highly significant decrease in the number of traversals across the original platform ( p < 0.001) ( Figure 1 I) and a considerable reduction in the time spent in the original platform quadrant ( p < 0.05) ( Figure 1 J), suggesting that the spatial memory ability of these mice was impaired.

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