highly significantp -value < 0.0001
While the 100 nM dose had no effect on the longevity of the N2 wild-type strain, worms treated with either 1 μM or 10 μM EAPB02303 displayed a highly significant lifespan extension compared to the control and vehicle DMSO groups ( p -value < 0.0001) ( Figure 1 A, Table 1 ).