Perioperative Marinobufagenin (MBG) Measurement May Improve Acute Kidney Injury Risk Assessment in Patients Undergoing Major Cardiac Surgery: A Proof-of-Concept Study.

The MBG levels displayed a decreasing trend in the whole population after surgery ( p = 0.02).

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In more detail, the MBG measured at either 4 h or 12 h after surgery was not statistically discriminant in such regard (AUC: 0.535 [0.381–0.685]; p = 0.71 and 0.545 [0.390–0.694], p = 0.64, respectively), while a barely significant capacity was observed for the measurements at the baseline (AUC: 0.688 [0.533–0.818]; p = 0.04) and 8 h after the CPB (AUC: 0.674 [0.518–0.806; p = 0.04)].

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