A preoperative dose of the pyridoindole AC102 improves the recovery of residual hearing in a gerbil animal model of cochlear implantation.

Cell Death Dis · 2024 · PMC11282255 · PMID 39060244

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Treatment with AC102 showed a concentration-dependent decrease of morphological cell damage, with a significant decrease at 30 μM (66.5 ± 9.51%, p = 0.028) and highly significant decrease at 100 μM (35.99 ± 9.51; p < 0.0001; Fig. 5b ).

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