10 A randomized trial in adults reported a highly significant survival benefit associated with the Ross procedure when compared with an aortic homograft. 11 However, the surgical technique is complex and associated with a long learning curve that has been estimated to be between 75 and 100 cases. 12 This factor, along with valid concerns about transforming univalve into bivalve disease, likely contributes to the low rate of adoption of this procedure. 10 This systematic review specifically focused on children undergoing the Ross procedure for whom outcomes are less well established.
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The Ross Procedure in Children and Infants: A Systematic Review With Pooled Analyses.
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