Barely Significant
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Hyper-reflective foci changes in RRMS under natalizumab therapy.

Front Immunol · 2024 · PMC11284017 · PMID 39076978

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a mild trendno p-value reported
Moving on to INL macular volume, the absence of any significant effect of natalizumab (even if a mild trend was observed in temporal inner ring, which calls for further studies with including more patients) is in line with the hypothesis of a chronic BRB dysfunction, but apparently not with a recent study ( 12 ).

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